Floxin

Pronunciation: oh-FLOX-a-sin
Generic Name: Ofloxacin
Brand Name: Floxin

Floxin is associated with an increased risk of tendon problems. These include pain, swelling, inflammation, and possible breakage of tendons. The risk of tendon problems is greater in patients who are older than 60 years, patients who take corticosteroids (eg, prednisone), and in those who have received kidney, heart, or lung transplants. The Achilles tendon in the back of the foot/ankle is most often affected. However, problems may also occur in other tendons (eg, in the shoulder, arm, hand). Problems may occur while you take Floxin or up to several months after you stop taking it.

Signs of tendon problems may include pain, soreness, redness, or swelling of a tendon or joint; bruising right after an injury in a tendon area; hearing or feeling a snap or pop in a joint or tendon area; or inability to move or bear weight on a joint or tendon area. Tell your doctor right away if you experience any of these symptoms while you take Floxin or within several months after you stop taking it.

Floxin may worsen muscle weakness and breathing problems in patients with myasthenia gravis. Do not take Floxin if you have a history of myasthenia gravis.

Floxin is used for:

Treating mild to moderate infections caused by certain bacteria.

Floxin is a fluoroquinolone antibiotic. It kills sensitive bacteria by stopping the production of essential proteins needed by the bacteria to survive.

Do NOT use Floxin if:

• you are allergic to any ingredient in Floxin or any other fluoroquinolone antibiotic (eg, ciprofloxacin)


• you have a history of myasthenia gravis


• you have abnormal blood electrolyte levels (eg, low potassium or magnesium) or a history of a certain type of irregular heartbeat (eg, QTc interval prolongation)


• you are taking certain antiarrhythmic medicines (eg, quinidine, procainamide, amiodarone, sotalol)


• you are taking a nonsteroidal anti-inflammatory drug (NSAIDs) (eg, ibuprofen) or typhoid oral vaccine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Floxin:

Some medical conditions may interact with Floxin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have diabetes, liver problems, or a recent heart attack


• if you or a family member have heart problems (eg, angina), irregular heartbeat (eg, QT prolongation), fast or slow heartbeat, or low potassium levels


• if you have Alzheimer disease, hardening in the arteries in the brain, seizures, increased pressure on the brain, or another central nervous system disorder


• if you have a history of joint or tendon problems; rheumatoid arthritis; kidney problems or decreased kidney function; or a heart, kidney, or lung transplant


• if your skin is sensitive to sunlight

Some MEDICINES MAY INTERACT with Floxin. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Antiarrhythmics (eg, amiodarone, disopyramide, dofetilide, quinidine, sotalol), cisapride, diuretics (eg, furosemide, hydrochlorothiazide), macrolide or ketolide antibiotics (eg, erythromycin, telithromycin), medicines for mental or mood disorders, medicines that may affect your heartbeat, phenothiazines (eg, chlorpromazine), or tricyclic antidepressants (eg, amitriptyline) because the risk of serious side effects, including irregular heartbeat and other heart problems, may be increased. Check with your doctor or pharmacist if you are unsure if any of your medicines may affect your heartbeat


• Corticosteroids (eg, prednisone) because the risk of tendon problems may be increased


• Foscarnet, NSAIDs (eg, ibuprofen), or tramadol because the risk of seizures may be increased


• Insulin or other medicines for diabetes (eg, glipizide) because the risk of low blood sugar may be increased


• Anticoagulants (eg, warfarin), procainamide, or theophylline because the risk of their side effects may be increased by Floxin


• Live typhoid vaccine because its effectiveness may be decreased by Floxin


• Aluminum salts (eg, aluminum hydroxide), iron salts (oral) (eg, ferrous sulfate), or magnesium salts (eg, magnesium hydroxide) because they may decrease Floxin's effectiveness. Take ofloxacin 2 hours before or 2 hours after these medicines to offset this effect

This may not be a complete list of all interactions that may occur. Ask your health care provider if Floxin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Floxin:

Use Floxin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Floxin by mouth with or without food.


• Take Floxin with a full glass of water (8 oz/240 mL). Drink several glasses of water daily, unless otherwise instructed by your doctor.


• Do not drink milk or eat dairy products, or take antacids, didanosine, sucralfate, or vitamins within 2 hours before or after taking Floxin.


• Floxin works best if it is taken at the same time each day.


• To clear up your infection completely, take Floxin for the full course of treatment. Keep taking it even if you feel better in a few days.


• If you miss a dose, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Floxin.

Important safety information:

• Floxin may cause drowsiness, dizziness, or light-headedness. These effects may be worse if you take it with alcohol or certain medicines. Use Floxin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Floxin may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Floxin. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.


• Diabetes patients - Floxin may affect your blood sugar when taken along with insulin or other medicines for diabetes. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.


• Tell your doctor or dentist that you take Floxin before you receive any medical or dental care, emergency care, or surgery.


• Floxin only works against bacteria; it does not treat viral infections (eg, the common cold).


• Long-term or repeated use of Floxin may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.


• If you experience pain or inflammation, or rupture a tendon during or shortly after taking ofloxacin, contact your health care provider immediately.


• Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.


• Be sure to use Floxin for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.


• Lab tests, including kidney function, may be performed while you use Floxin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Use Floxin with caution in the ELDERLY; they may be more sensitive to its effects (eg, tendon problems), especially if they take corticosteroids (eg, prednisone). They may also be more sensitive to other effects (eg, irregular heartbeat).


• Floxin should not be used in CHILDREN younger than 18 years; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking Floxin while you are pregnant. Floxin is found in breast milk. Do not breast-feed while taking Floxin.

Possible side effects of Floxin:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; headache; loss of appetite; nausea; sensitivity to sunlight; trouble sleeping; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); agitation; anxiety; bizarre behavior; bloody stools; burning, numbness, tingling, pain, or weakness of the arms, hands, legs, or feet; change in sense of touch or temperature; confusion; convulsions; dark urine; decreased urination; depression; diarrhea (severe or continuing); difficulty swallowing; excessive urination, thirst, or hunger; fainting; fast or irregular heartbeat; fatigue; fever, chills, or unusual cough; hallucinations; joint pain or swelling; light-headedness; loss of consciousness; mental or mood changes; muscle pain or weakness; nervousness; nightmares; pale stools; red, swollen, blistered, or peeling skin; restlessness; seizures; shortness of breath; shock (pale skin); sleeplessness; severe or persistent stomach pain or cramps; shortness of breath or trouble breathing; suicidal thoughts; tendon pain, inflammation, or swelling; tightness of the throat; tremors; unusual bruising or bleeding; unusual tiredness or weakness; urination problems; vaginal irritation or discharge; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Floxin side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org ), or emergency room immediately. Symptoms may include facial swelling and numbness; hot and cold flushes; mild to moderate disorientation; slurring of speech.

Proper storage of Floxin:

Store Floxin below 86 degrees F (30 degrees C). Store in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Floxin out of the reach of children and away from pets.

General information:

• If you have any questions about Floxin, please talk with your doctor, pharmacist, or other health care provider.


• Floxin is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is summary only. It does not contain all information about Floxin. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Floxin resources

• Floxin Side Effects (in more detail)
• Floxin Dosage
• Floxin Use in Pregnancy & Breastfeeding
• Drug Images
• Floxin Drug Interactions
• Floxin Support Group
• 1 Review for Floxin - Add your own review/rating

• Floxin Consumer Overview


• Floxin Advanced Consumer (Micromedex) - Includes Dosage Information


• Floxin Prescribing Information (FDA)


• Ofloxacin Prescribing Information (FDA)


• Ofloxacin Monograph (AHFS DI)


• Ofloxacin Professional Patient Advice (Wolters Kluwer)


• Floxin I.V.

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Herpes Zoster Meningitis Medications

There are currently no drugs listed for "Herpes Zoster Meningitis".

Learn more about Herpes Zoster Meningitis

Micromedex Care Notes:

• Herpes Zoster

Medical Encyclopedia:

• Shingles

Drug List:

Ala-Quin

Generic Name: clioquinol and hydrocortisone topical (KLYE oh KWIN ol and HYE droe KOR ti sone TOP ik al)

Brand Names: Ala-Quin

What is clioquinol and hydrocortisone?

Clioquinol topical fights bacteria and prevents fungus from growing on your skin.

Hydrocortisone is a topical steroid. It reduces the actions of chemicals in the body that cause inflammation, redness, and swelling.

The combination of clioquinol and hydrocortisone is used to treat skin redness and itching caused by skin infections, eczema, or other skin conditions.

Clioquinol and hydrocortisone may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about clioquinol and hydrocortisone?

Use this medication exactly as it was prescribed for you. Do not use it in larger amounts or for longer than recommended by your doctor.

Do not cover the wound with a bandage dressing, unless your doctor has told you to. If you are treating diaper rash on an infant, do not use tight-fitting diapers or plastic pants. Covering the skin where this medicine has been applied can cause your body to absorb the steroid contained in the medication. Absorption of a steroid can cause unwanted side effects, especially in children. Stop using this medication and get emergency medical help if you think you have used too much medicine, or if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects are more likely, and you may have none at all. Talk to your doctor about any side effect that seems unusual or is especially bothersome.

Call your doctor if your symptoms do not improve or if they get worse during the first 7 days of treatment with clioquinol and hydrocortisone.

What should I discuss with my health care provider before using clioquinol and hydrocortisone?

Before using this medication, tell your doctor if you are pregnant or breast-feeding.

This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether clioquinol and hydrocortisone passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. If you use clioquinol and hydrocortisone on a child, do not use the medication for longer than the child's doctor has prescribed.

How should I use clioquinol and hydrocortisone?

Use this medication exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor.

Before you apply clioquinol and hydrocortisone, use soap and water to wash the skin area you plan to treat.

Apply a thin layer of medication to the skin and rub it in gently.

Do not cover the wound with a bandage dressing, unless your doctor has told you to. If you are treating diaper rash on an infant, do not use tight-fitting diapers or plastic pants. Covering the skin where this medicine has been applied can cause your body to absorb the steroid contained in the medication. Absorption of a steroid can cause unwanted side effects, especially in children. Wash your hands thoroughly with soap and water after you apply this medication.

If you need to remove the medicine, wash it off with water and mild soap.

Call your doctor if your symptoms do not improve or if they get worse during the first 7 days of treatment with clioquinol and hydrocortisone.

Store this medication at room temperature away from moisture and heat. Do not allow the medicine to freeze.

What happens if I miss a dose?

Use the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and use the medicine at the next regularly scheduled time. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine, or if anyone has accidentally swallowed it.

An overdose of clioquinol and hydrocortisone applied to the skin is not expected to produce life-threatening symptoms.

What should I avoid while using clioquinol and hydrocortisone?

Avoid getting this medication in your eyes, mouth, and nose, or on your lips. If it does get into any of these areas, wash with water. Do not give the medicine to another person, even if you think they have the same skin condition you have. Do not use this medication for any skin condition that has not been checked by your doctor.

Avoid using skin products that can cause irritation, such as harsh soaps or shampoos or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime. Do not use other medicated skin products unless your doctor has told you to.

Clioquinol and hydrocortisone may stain skin, clothing, and other fabrics it comes in contact with. Take care not to get this medicine on your clothes, carpet, or bed linens.

Clioquinol and hydrocortisone side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Other less serious side effects are more likely to occur, such as:

• 
  

  mild stinging or burning where the medicine is applied.

  
  

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect clioquinol and hydrocortisone?

It is not likely that other drugs you take orally or inject will have an effect on topically applied clioquinol and hydrocortisone. But many drugs can interact with each other. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

More Ala-Quin resources

• Ala-Quin Side Effects (in more detail)
• Ala-Quin Use in Pregnancy & Breastfeeding
• Ala-Quin Drug Interactions
• Ala-Quin Support Group
• 0 Reviews for Ala-Quin - Add your own review/rating

• Ala-Quin Cream MedFacts Consumer Leaflet (Wolters Kluwer)

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• Dermatitis
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• Pruritus

Where can I get more information?

• Your pharmacist can provide more information about clioquinol and hydrocortisone.

See also: Ala-Quin side effects (in more detail)

methyl aminolevulinate Topical application

METH-il a-mee-noe-lev-ue-LIN-ate

Commonly used brand name(s)

In the U.S.

• Metvixia

Available Dosage Forms:

• Cream

Therapeutic Class: Photosensitizing Agent

Uses For methyl aminolevulinate

Methyl aminolevulinate is used with photodynamic therapy (light treatment) to treat actinic keratosis (AK) on the face and scalp. Actinic keratoses are skin lesions or growths in areas where the skin has been exposed to the sun. AK normally occurs in older patients with light-colored skin. methyl aminolevulinate is only used for AK skin lesions that are thin and light in color.

methyl aminolevulinate is available only with your doctor's prescription.

Before Using methyl aminolevulinate

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For methyl aminolevulinate, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to methyl aminolevulinate or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of methyl aminolevulinate in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of methyl aminolevulinate in the elderly.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of methyl aminolevulinate. Make sure you tell your doctor if you have any other medical problems, especially:

• Allergy to almond oil or


• allergy to peanut oil or


• allergy to porphyrins (e.g., porfimer [Photofrin®], verteporfin [Visudyne®]) or


• photosensitivity (skin sensitive to sunlight), history of—Should not be used in patients with these conditions.

• Bleeding problems or


• Skin cancer or other skin lesions, history of—Use with caution. May cause side effects to become worse.

Proper Use of methyl aminolevulinate

Methyl aminolevulinate will be applied to your skin in a clinic or doctor's office. You will receive two treatments with methyl aminolevulinate spaced 1 week apart.

Methyl aminolevulinate is for use on the skin only. Do not get it in your eyes, nose, or mouth. If it does get on these areas, tell your doctor right away.

Precautions While Using methyl aminolevulinate

It is very important that your doctor check your progress three months after the treatment. This will allow your doctor to see if the medicine is working properly and to check for unwanted effects.

methyl aminolevulinate causes the treated areas of your skin to be more sensitive to light. Avoid exposure to sunlight or bright indoor light for 3 hours after the medicine is applied to your skin. This includes medical examination lights, operating room lights, tanning beds, or any lights that are close to you. You should also avoid exposure to sunlight or bright indoor light on the treated skin for 2 days after the light treatment (photodynamic therapy). Cover the treated areas of your skin. If you must go out during daylight hours, wear a protective hat or clothing. Check with your doctor if you have questions about this.

Avoid cold temperatures for 3 hours after the medicine is applied to your skin. Wear warm clothing and cover the treated area if you are in cold places.

methyl aminolevulinate Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Breakdown of the skin


• irritation and redness of the skin


• scabbing


• swelling of the eyelid


• swelling of the skin

Less common

• Discharge at the site of application


• sores on the skin that do not heal

Incidence not known

• Blistering, burning, crusting, dryness, or flaking of the skin


• blurred vision or other change in vision


• eye redness, irritation, or pain


• hives or welts


• itching, scaling, or severe redness of the skin


• persistent non-healing sore


• pink growth on the skin


• reddish patch or irritated area on the skin


• seeing flashes or sparks of light


• seeing floating spots before the eyes, or a veil or curtain appearing across part of the vision


• shiny bump on the skin


• skin rash, encrusted, scaly and oozing


• white, yellow, or waxy scar-like area on the skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

• Darkening of the skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: methyl aminolevulinate Topical application side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More methyl aminolevulinate Topical application resources

• Methyl aminolevulinate Topical application Side Effects (in more detail)
• Methyl aminolevulinate Topical application Use in Pregnancy & Breastfeeding
• Methyl aminolevulinate Topical application Drug Interactions
• Methyl aminolevulinate Topical application Support Group
• 0 Reviews for Methyl aminolevulinate Topical application - Add your own review/rating

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• Actinic Keratosis

TCP Antiseptic Cream

1. Name Of The Medicinal Product

TCP First Aid Antiseptic Cream

2. Qualitative And Quantitative Composition

TCP First Aid Antiseptic Cream contains:

TCP Liquid Antiseptic 25% w/w, Chloroxylenol 0.5% w/w and Triclosan 0.3% w/w. TCP Liquid Antiseptic is an aqueous solution of Phenol 0.175% w/v, halogenated phenols 0.68% w/v and Sodium Salicylate 0.052% w/v.

3. Pharmaceutical Form

Topical cream.

4. Clinical Particulars

4.1 Therapeutic Indications

Treatment of minor cuts, grazes, scratches, insect bites and stings, spots, pimples and blisters.

TCP First Aid Antiseptic Cream can also be used as a first aid antiseptic hand cream.

Topical administration.

4.2 Posology And Method Of Administration

Adults, children and the elderly:

Minor cuts, grazes, scratches, insect bites and stings:

Clean wound and surrounding skin and apply the cream direct or on to a dressing.

Spots, pimples and blisters:

Apply direct and rub in gently.

TCP First Aid Antiseptic Cream can also be used as a first aid antiseptic hand cream.

4.3 Contraindications

Hypersensitivity to any of the active ingredients.

4.4 Special Warnings And Precautions For Use

If symptoms persist, consult your doctor.

For external use only.

Keep out of the reach and sight of children.

4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction

None known.

4.6 Pregnancy And Lactation

There is no experience in the use of the product in pregnancy and lactation, but the product has been widely used for many years with no adverse effects.

4.7 Effects On Ability To Drive And Use Machines

None.

4.8 Undesirable Effects

Use in allergic skin conditions should be avoided.

4.9 Overdose

TCP First Aid Antiseptic Cream is for topical use only and overdose is considered unlikely.

5. Pharmacological Properties

5.1 Pharmacodynamic Properties

Halogenated phenols act on all pathogenic micro-organisms similarly and to approximately the same degree i.e. they are non-specific; and their activity is not appreciably reduced by the presence of relatively large amounts of non-living organic matter; their relatively simple chemical constitution means that their use is not liable to encourage the emergence of strains of micro-organisms adapted to resist their action.

5.2 Pharmacokinetic Properties

TCP First Aid Antiseptic Cream is for topical use only. Systemic absorption from this topical dosage form is considered unlikely.

5.3 Preclinical Safety Data

Not applicable.

6. Pharmaceutical Particulars

6.1 List Of Excipients

Stearic Acid

Isopropyl Palmitate

Cetyl Alcohol

Cetyl Wax Esters

Glyceryl Monostearate

Sodium Lauryl Sulphate

Carbomer

Glycerol

Sodium Edetate

Potassium Hydroxide

Demineralised Water

Fragrance EAG 5276

6.2 Incompatibilities

None known.

6.3 Shelf Life

36 months.

6.4 Special Precautions For Storage

Do not store above 25°C.

6.5 Nature And Contents Of Container

Collapsible aluminium tubes, internally lacquered, fitted with white polyethylene wadless caps.

Tubes of 30g and 60g.

6.6 Special Precautions For Disposal And Other Handling

Not applicable.

7. Marketing Authorisation Holder

Chefaro UK Ltd.

4th Floor, Hamilton House

Mabledon Place, Bloomsbury

LONDON,

WC1H 9BB

United Kingdom

8. Marketing Authorisation Number(S)

PL 02855/0020

9. Date Of First Authorisation/Renewal Of The Authorisation

16th November 2004

10. Date Of Revision Of The Text

14th November 2010

Panadol ActiFast Soluble Tablets

1. Name Of The Medicinal Product

Panadol ActiFast Soluble Tablets

Or

Panadol Soluble 500 mg Tablets

2. Qualitative And Quantitative Composition

Each tablet contains Paracetamol Ph.Eur. 500.0 mg

3. Pharmaceutical Form

Effervescent tablet (Tablets).

4. Clinical Particulars

4.1 Therapeutic Indications

Paracetamol is a mild analgesic and antipyretic, and is recommended for the treatment of most painful and febrile conditions, for example, headache including migraine and tension headaches, toothache, backache, rheumatic and muscle pains, dysmenorrhoea, sore throat, and for relieving the fever, aches and pains of colds and flu.

4.2 Posology And Method Of Administration

Adults and the elderly:

1 -2 tablets in at least half a tumbler of water, up to 4 times daily as required.

Children:

6 - 12 years: ½ - 1 tablet dissolved in water up to 4 times daily. Not recommended for children under the age of 6 years.

Doses of paracetamol should not be given more frequently than every 4 hours, and not more than 4 doses should be given in any 24 hour period.

Children should not be given paracetamol for more than 3 days without consulting a doctor.

Oral administration only.

4.3 Contraindications

Hypersensitivity to paracetamol or any of the other constituents.

4.4 Special Warnings And Precautions For Use

Care is advised in the administration of paracetamol to patients with renal or hepatic impairment. The hazard of overdose is greater in those with non-cirrhotic alcoholic liver disease.

Do not exceed the stated dose.

Patients should be advised to consult their doctor if their headaches become persistent.

Patients should be advised not to take other paracetamol-containing products concurrently.

This medicinal product contains 427 mg of sodium per tablet and should not be taken by patients on a low sodium diet.

Patients with rare hereditary problems of fructose intolerance should not take this medicine.

If symptoms persist consult your doctor.

Keep out of the reach and sight of children.

Pack Label:

Immediate medical advice should be sought in the event of an overdose, even if you feel well.

Do not take with any other paracetamol containing products.

Patient Information Leaflet:

Immediate medical advice should be sought in the event of an overdose, even if you feel well, because of the risk of delayed, serious liver damage.

4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction

The speed of absorption of paracetamol may be increased by metoclopramide or domperidone and absorption reduced by colestyramine. The anticoagulant effect of warfarin and other coumarins may be enhanced by prolonged regular daily use of paracetamol with increased risk of bleeding; occasional doses have no significant effect.

4.6 Pregnancy And Lactation

Epidemiological studies in human pregnancy have shown no ill effects due to paracetamol used in the recommended dosage, but patients should follow the advice of their doctor regarding its use. Paracetamol is excreted in breast milk but not in a clinically significant amount. Available published data do not contraindicate breast feeding.

4.7 Effects On Ability To Drive And Use Machines

None.

4.8 Undesirable Effects

Adverse events of paracetamol from historical clinical trial data are both infrequent and from small patient exposure. Accordingly, events reported from extensive post-marketing experience at therapeutic/labelled dose and considered attributable are tabulated below by system class. Due to limited clinical trial data, the frequency of these adverse events is not known (cannot be estimated from available data), but post-marketing experience indicates that adverse reactions to paracetamol are rare and serious reactions are very rare.

Post marketing data

Body System	Undesirable effect
Blood and lymphatic system disorders	Thrombocytopenia Agranulocytosis
Immune system disorders	Anaphylaxis Cutaneous hypersensitivity reactions including skin rashes, angiodema and Stevens Johnson syndrome/toxic epidermal necrolysis
Respiratory, thoracic and mediastinal disorders	Bronchospasm*
Hepatobiliary disorders	Hepatic dysfunction

* There have been cases of bronchospasm with paracetamol, but these are more likely in asthmatics sensitive to aspirin or other NSAIDs.

4.9 Overdose

Liver damage is possible in adults who have taken 10 g or more of paracetamol. Ingestion of 5 g or more of paracetamol may lead to liver damage if the patient has risk factors (see below).

Risk Factors:

If the patient

• Is on long term treatment with carbamazepine, phenobarbitone, phenytoin, primidone, rifampicin, St John's Wort or other drugs that induce liver enzymes.

Or

• Regularly consumes ethanol in excess of recommended amounts.

Or

• Is likely to be glutathione deplete e.g. eating disorders, cystic fibrosis, HIV infection, starvation, cachexia.

Symptoms

Symptoms of paracetamol overdose in the first 24 hours are pallor, nausea, vomiting, anorexia and abdominal pain. Liver damage may become apparent 12 to 48 hours after ingestion. Abnormalities of glucose metabolism and metabolic acidosis may occur. In severe poisoning, hepatic failure may progress to encephalopathy, haemorrhage, hypoglycaemia, cerebral oedema and death. Acute renal failure with acute tubular necrosis, strongly suggested by loin pain, haematuria and proteinuria, may develop even in the absence of severe liver damage. Cardiac arrhythmias and pancreatitis have been reported.

Management

Immediate treatment is essential in the management of paracetamol overdose. Despite a lack of significant early symptoms, patients should be referred to hospital urgently for immediate medical attention. Symptoms may be limited to nausea or vomiting and may not reflect the severity of overdose or the risk of organ damage. Management should be in accordance with established treatment guidelines, see BNF overdose section.

Treatment with activated charcoal should be considered if the overdose has been taken within 1 hour. Plasma paracetamol concentration should be measured at 4 hours or later after ingestion (earlier concentrations are unreliable). Treatment with N-acetylcysteine may be used up to 24 hours after ingestion of paracetamol, however, the maximum protective effect is obtained up to 8 hours post-ingestion. The effectiveness of the antidote declines sharply after this time. If required the patient should be given intravenous N-acetylcysteine, in line with the established dosage schedule. If vomiting is not a problem, oral methionine may be a suitable alternative for remote areas, outside hospital. Management of patients who present with serious hepatic dysfunction beyond 24h from ingestion should be discussed with the NPIS or a liver unit.

High doses of sodium bicarbonate may be expected to induce gastrointestinal symptoms including belching and nausea. In addition, high doses of sodium bicarbonate may cause hypernatraemia; electrolytes should be monitored and patients managed accordingly.

5. Pharmacological Properties

5.1 Pharmacodynamic Properties

Paracetamol is a well established analgesic.

5.2 Pharmacokinetic Properties

Paracetamol is rapidly and almost completely absorbed from the gastro-intestinal tract. Concentration of the drug in plasma reaches a peak in 30 - 60 minutes and the plasma half-life is 1 - 4 hours.

Paracetamol is relatively uniformly distributed throughout most body fluids and exhibits variable protein binding. Excretion is almost exclusively renal in the form of conjugated metabolites.

5.3 Preclinical Safety Data

There are no pre-clinical data of relevance to the prescriber which are additional to that already included in other sections of the SPC.

6. Pharmaceutical Particulars

6.1 List Of Excipients

Sorbitol powder, saccharin sodium, sodium bicarbonate, polyvidone, sodium lauryl sulphate, dimeticone, citric acid, sodium carbonate.

6.2 Incompatibilities

There are no known incompatibilities with paracetamol.

6.3 Shelf Life

48 months.

6.4 Special Precautions For Storage

Store below 25°C.

6.5 Nature And Contents Of Container

PPFP or surlyn laminate strips further packed into cardboard cartons containing 4, 12, 16, 20, 24, 48, 60 or 100 tablets.

6.6 Special Precautions For Disposal And Other Handling

Not applicable.

7. Marketing Authorisation Holder

SmithKline Beecham (SWG) Limited

980 Great West Road

Brentford

Middlesex

TW8 9GS

United Kingdom

Trading as Sterling Health or GlaxoSmithKline Consumer Healthcare or SmithKline Beecham International, Brentford, TW8 9GS.

8. Marketing Authorisation Number(S)

PL 00071/0072R

9. Date Of First Authorisation/Renewal Of The Authorisation

Date of First Grant	12.01.82
Date of last Renewal	12.01.92
	12.05.97

10. Date Of Revision Of The Text

04.11.10

Para-Time S.R.

Generic Name: papaverine (Oral route)

pa-PAV-er-een

Commonly used brand name(s)

In the U.S.

• Papacon


• Para-Time S.R.


• Pavacot

Available Dosage Forms:

• Capsule, Extended Release


• Tablet

Therapeutic Class: Peripheral Vasodilator

Uses For Para-Time S.R.

Papaverine belongs to the group of medicines called vasodilators. Vasodilators cause blood vessels to expand, thereby increasing blood flow. This medicine is used to treat problems resulting from poor blood circulation.

Papaverine is available only with your doctor's prescription.

Before Using Para-Time S.R.

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Although there is no specific information comparing use of papaverine in children with use in other age groups, this medicine is not expected to cause different side effects or problems in children than it does in adults.

Geriatric

Papaverine may reduce tolerance to cold temperatures in elderly patients.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Ginkgo

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Angina (chest pain) or


• Glaucoma or


• Heart disease or


• Myocardial infarction (heart attack), recent, or


• Stroke, recent—The chance of unwanted effects may be increased.

Proper Use of papaverine

This section provides information on the proper use of a number of products that contain papaverine. It may not be specific to Para-Time S.R.. Please read with care.

If this medicine upsets your stomach, it may be taken with meals, milk, or antacids.

For patients taking the extended-release capsule form of this medicine:

• Swallow the capsule whole. Do not crush, break, or chew before swallowing. However, if the capsule is too large to swallow, you may mix the contents with jam or jelly and swallow without chewing.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (extended-release capsules):
  
  • Adults: 150 milligrams (mg) every twelve hours. The dose may be increased to 150 mg every eight hours or 300 mg every twelve hours.
  
  


• For oral dosage form (tablets):
  
  • Adults: 100 to 300 milligrams (mg) three to five times a day.
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Para-Time S.R.

It may take some time for this medicine to work. If you feel that the medicine is not working, do not stop taking it on your own. Instead, check with your doctor.

The helpful effects of this medicine may be decreased if you smoke. If you have any questions about this, check with your doctor.

Dizziness may occur, especially when you get up from a lying or sitting position or climb stairs. Getting up slowly may help. If this problem continues or gets worse, check with your doctor.

Para-Time S.R. Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

• Abdominal pain or tenderness


• blurred or double vision


• change in ability to see colors, especially blue or yellow


• clay-colored stools


• dark urine


• decreased appetite


• deep, slow breathing


• drowsiness


• fatigue


• fever


• headache


• insomnia


• itching


• loss of appetite


• nausea and vomiting


• painful or prolonged erection of the penis


• skin rash


• swelling of the feet or lower legs


• trouble with breathing


• unusual tiredness or weakness


• vomiting


• weakness


• yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

• Constipation


• diarrhea


• dizziness or lightheadedness


• fainting


• fast, pounding, or irregular heartbeat or pulse


• feeling of constant movement of self or surroundings


• flushed face


• itching skin


• nervousness


• palpitations


• pounding in the ears


• sensation of spinning


• sleepiness or unusual drowsiness


• slow or fast heartbeat

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Para-Time S.R. side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Para-Time S.R. resources

• Para-Time S.R. Side Effects (in more detail)
• Para-Time S.R. Use in Pregnancy & Breastfeeding
• Drug Images
• Para-Time S.R. Drug Interactions
• Para-Time S.R. Support Group
• 0 Reviews · Be the first to review/rate this drug

fulvestrant Intramuscular

ful-VES-trant

Commonly used brand name(s)

In the U.S.

• Faslodex

Available Dosage Forms:

• Solution

Therapeutic Class: Antiestrogen

Uses For fulvestrant

Fulvestrant injection is used to treat metastatic breast cancer (cancer that has spread) that is hormone-receptor positive in women who have already stopped menstruating (postmenopausal). It is used for women who have breast cancer that has not improved after using other cancer medicines.

Many of the breast cancer tumors will grow when estrogen is available in the body. fulvestrant blocks the effects of the estrogen hormone in the body. As a result, the amount of estrogen that the tumor is exposed to is reduced, which will limit the growth of the tumor.

fulvestrant is available only with your doctor's prescription.

Before Using fulvestrant

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For fulvestrant, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to fulvestrant or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of fulvestrant injection in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of fulvestrant injection in the elderly.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	D	Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of fulvestrant. Make sure you tell your doctor if you have any other medical problems, especially:

• Bleeding problems or


• Thrombocytopenia (low platelets in the blood)—Use with caution. May make these conditions worse.

• Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Proper Use of fulvestrant

Medicines used to treat cancer are very strong and can have many side effects. Before receiving fulvestrant, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

You will receive fulvestrant while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you fulvestrant. fulvestrant is given as a shot into one of your buttocks muscles.

Fulvestrant injection comes with patient instructions. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Missed Dose

fulvestrant needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

Precautions While Using fulvestrant

It is very important that your doctor check your progress at regular visits to make sure that the medicine is working properly. Blood tests may be needed to check for unwanted effects.

It is unlikely that a postmenopausal woman may become pregnant. But, you should know that using fulvestrant while you are pregnant could harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while receiving the medicine, tell your doctor right away.

fulvestrant may cause you to have bleeding from the vagina, especially when you first start using it. If the bleeding continues or is bothersome, check with your doctor right away.

Cancer medicines can cause nausea or vomiting, even after receiving medicines to prevent it. If you have nausea and vomiting after receiving fulvestrant, talk to your doctor or nurse about ways to control these effects.

fulvestrant Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

• Bloating or swelling of the face, arms, hands, lower legs, or feet


• rapid weight gain


• tingling of the hands or feet


• unusual weight gain or loss

Less common

• Difficult or labored breathing


• shortness of breath


• tightness in the chest


• wheezing

Incidence not known

• Black, tarry stools


• chest pain


• chills


• cough


• fever


• flushing or redness of the skin


• hives or welts


• itching


• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs


• pain in the chest, groin, or legs, especially the calves


• painful or difficult urination


• severe and sudden headache


• skin rash


• slurred speech


• sore throat


• sores, ulcers, or white spots on the lips or in the mouth


• sudden loss of coordination


• sudden and severe weakness or numbness in the arm or leg


• sudden unexplained shortness of breath


• swollen glands


• unusual bleeding or bruising


• unusual tiredness or weakness


• vaginal bleeding


• vision changes

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Back pain


• bladder pain


• bloody or cloudy urine


• body aches or pain


• bone pain


• burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings


• depression


• diarrhea


• difficulty having a bowel movement (stool)


• difficulty with moving


• dizziness


• dryness or soreness of the throat


• feeling faint, dizzy, or lightheaded


• feeling of warmth or heat


• feeling sad or empty


• frequent urge to urinate


• general feeling of discomfort or illness


• headache


• hoarseness


• irritability


• joint pain


• lack or loss of appetite


• lack or loss of strength


• loss of interest or pleasure


• lower back or side pain


• muscle aches and pains


• muscle stiffness


• nausea


• pain at the injection site


• pain in the arms or legs


• pelvic pain


• shivering


• skin rash


• stomach pain


• sudden sweating


• tender, swollen glands in the neck


• trouble concentrating


• trouble with swallowing


• unable to sleep


• voice changes


• vomiting


• weight loss

Less common

• Nervousness


• pain, swelling, or redness in the joints


• pale skin

Incidence not known

• Dizziness or lightheadedness


• feeling of constant movement of self or surroundings


• sensation of spinning

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: fulvestrant Intramuscular side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More fulvestrant Intramuscular resources

• Fulvestrant Intramuscular Side Effects (in more detail)
• Fulvestrant Intramuscular Use in Pregnancy & Breastfeeding
• Fulvestrant Intramuscular Support Group
• 3 Reviews for Fulvestrant Intramuscular - Add your own review/rating

Compare fulvestrant Intramuscular with other medications

• Breast Cancer
• Breast Cancer, Metastatic

Iotalamic Acid

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

V08AA04

CAS registry number (Chemical Abstracts Service)

0002276-90-6

Chemical Formula

C11-H9-I3-N2-O4

Molecular Weight

613

Therapeutic Category

Contrast medium

Chemical Name

Benzoic acid, 3-(acetylamino)-2,4,6-triiodo-5-[(methylamino)carbonyl]-

Foreign Names

• Acidum Iotalamicum (Latin)
• Iotalaminsäure (German)
• Acide iotalamique (French)
• Acido iotalamico (Spanish)

Generic Names

• Acide iotalamique (OS: DCF)
• Acido iotalamico (OS: DCIT)
• Iotalamic Acid (OS: JAN, BAN)
• Iothalamic Acid (OS: USAN)
• MI 216 (IS: Mallinckrodt)
• Acidum iotalamicum (PH: Ph. Eur. 6)
• Iotalamic Acid (PH: BP 2010, JP XIV, Ph. Eur. 6)
• Iotalaminsäure (PH: Ph. Eur. 6)
• Iotalamique (acide) (PH: Ph. Eur. 6)
• Iothalamic Acid (PH: USP 32)
• Meglumine Iotalamate (OS: BANM)
• Meglumine Iotalamate Injection (OS: JAN)
• Iotalamic acid, comp. with N-methylglucamine (IS)
• Meglumine Iothalamate (IS)
• Iothalamate Meglumine Injection (PH: USP 32)
• Meglumine Iotalamate Injection (PH: JP XIV)
• Meglumine Iothalamate Injection (PH: BP 1999)
• Sodium Iotalamate (OS: BANM)
• Natrium iotalamat (IS)
• Sodium Iothalamate (IS)
• Iothalamate Sodium Injection (PH: USP 32)
• Sodium Iothalamate Injection (PH: JP XIV, BP 1999)

Brand Names

• Conray 24 36 60%
  Ewopharma, Czech Republic



• Conray
  Daiichi Sankyo, Japan; Mallinckrodt, Argentina; Mallinckrodt, Australia; Mallinckrodt, Peru; Mallinckrodt, United States; Tyco, Canada



• Cysto-Conray
  Mallinckrodt, Argentina; Mallinckrodt, United States; Tyco, Canada



• Conray
  Daiichi Sankyo, Japan; Mallinckrodt, Argentina

International Drug Name Search

Glossary

BAN	British Approved Name
BANM	British Approved Name (Modified)
DCF	Dénomination Commune Française
DCIT	Denominazione Comune Italiana
IS	Inofficial Synonym
JAN	Japanese Accepted Name
OS	Official Synonym
PH	Pharmacopoeia Name
Rec.INN	Recommended International Nonproprietary Name (World Health Organization)
USAN	United States Adopted Name

Click for further information on drug naming conventions and International Nonproprietary Names.

Pedi-Dri

Generic Name: nystatin topical (nye STAT in)

Brand Names: Mycostatin Topical, Nyamyc, Nystop, Pedi-Dri, Pediaderm AF

What is Pedi-Dri (nystatin topical)?

Nystatin is an antifungal medication. Nystatin prevents fungus from growing on your skin.

Nystatin topical (for the skin) is used to treat skin infections caused by yeast.

Nystatin topical is not for use to treat a vaginal yeast infection.

Nystatin topical may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Pedi-Dri (nystatin topical)?

Do not use nystatin topical to treat any skin condition that has not been checked by your doctor. Nystatin topical (for the skin) is not for use to treat a vaginal yeast infection. Avoid getting this medication in your eyes or mouth. If this does happen, rinse with water.

Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared.

Call your doctor if your symptoms do not improve, or if they get worse while using nystatin topical. Do not share this medication with another person, even if they have the same symptoms you have.

What should I discuss with my healthcare provider before using Pedi-Dri (nystatin topical)?

You should not use nystatin topical if you have ever had an allergic reaction to it.

FDA pregnancy category C. It is not known whether nystatin topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether nystatin topical passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use Pedi-Dri (nystatin topical)?

Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Do not use nystatin topical to treat any skin condition that has not been checked by your doctor. Wash your hands before and after using this medication.

Clean and dry the skin before you apply nystatin topical.

Do not cover treated skin with bandages or dressings that do not allow air circulation unless your doctor tells you to.

Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared.

Call your doctor if your symptoms do not improve, or if they get worse while using nystatin topical. Do not share this medication with another person, even if they have the same symptoms you have. Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Pedi-Dri (nystatin topical)?

Avoid getting this medication in your eyes or mouth. If this does happen, rinse with water.

Avoid wearing tight-fitting, synthetic clothing (such as nylon) that doesn't allow air circulation. Wear clothing made of loose cotton and other natural fibers until your infection is healed.

Pedi-Dri (nystatin topical) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using nystatin topical and call your doctor at once if you have severe burning, itching, rash, pain, or other irritation where the medicine is applied.

Less serious side effects may include mild itching or irritation.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Pedi-Dri (nystatin topical)?

It is not likely that other drugs you take orally or inject will have an effect on topically applied nystatin topical. But many drugs can interact with each other. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Pedi-Dri resources

• Pedi-Dri Side Effects (in more detail)
• Pedi-Dri Use in Pregnancy & Breastfeeding
• Pedi-Dri Support Group
• 1 Review for Pedi-Dri - Add your own review/rating

Compare Pedi-Dri with other medications

• Cutaneous Candidiasis
• Vaginal Yeast Infection

Where can I get more information?

• Your pharmacist can provide more information about nystatin topical.

See also: Pedi-Dri side effects (in more detail)